Recombinant Rat IL-1 beta/IL1B Protein (mature form) (Active)
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Recombinant Rat IL-1 beta/IL1B Protein (mature form) (Active)

Cat. No : CDRP-01262
size:
Target Information
Target Name IL-1 beta/IL1B
Synonyms Interleukin-1 Beta; IL-1 Beta; Il1b
UniProt ID Q9WVG1
Accession Q63264-1
Product Details
Expression Host E.coli
Species Rat
Tag None
Molar Mass 17.4 kDa
Sequence Met 1-Ala 132
Application Cell Culture
Background
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1/Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile 40 mM Tris, 0.15 M NaCl, pH7.8
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.