Products
Online Inquiry
Recombinant Rat APCS/SAP Protein (His Tag)
Cat. No : CDRP-01210
size:
Target Information | |
---|---|
Target Name | APCS/SAP |
Synonyms | Sap |
UniProt ID | Q9NPC6 |
Accession | P23680 |
Product Details | |
---|---|
Expression Host | HEK293 Cells |
Species | Rat |
Tag | C-His |
Molar Mass | 25.3 kDa |
Sequence | Met 1-Ala 342 |
Background |
---|
Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations. |
Properties | |
---|---|
Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile PBS, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.