Products
Online Inquiry
Recombinant Mouse TNF-alpha/TNFA Protein (aa 80-235) (Active)
Cat. No : CDRP-01160
size:
| Target Information | |
|---|---|
| Target Name | TNF-alpha/TNFA |
| Synonyms | Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2 |
| UniProt ID | Q9BXJ1 |
| Accession | NP_038721.1 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Mouse |
| Tag | None |
| Molar Mass | 17 kDa |
| Sequence | Val 77-Leu 235 |
| Application | Cell Culture |
| Background |
|---|
| Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment. |
| Properties | |
|---|---|
| Purity | >99% as determined by reducing SDS-PAGE. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.