Recombinant Mouse THSD1/TMTSP Protein (His Tag)
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Recombinant Mouse THSD1/TMTSP Protein (His Tag)

Cat. No : CDRP-01146
size:
Target Information
Target Name THSD1/TMTSP
Synonyms Thrombospondin Type-1 Domain-Containing Protein 1; Transmembrane Molecule with Thrombospondin Module; THSD1; TMTSP
UniProt ID Q96PD4
Accession NP_062522.1
Product Details
Expression Host HEK293 Cells
Species Mouse
Tag C-His
Molar Mass 45 kDa
Sequence Met 1-Val 423
Background
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein which contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. in vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.