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Recombinant Mouse SerpinF2/SERPINF2 Protein (His Tag)
Cat. No : CDRP-01126
size:
| Target Information | |
|---|---|
| Target Name | SerpinF2/SERPINF2 |
| Synonyms | Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-plasmin inhibitor; Alpha-2-PI; Serpin F2; Serpinf2 |
| UniProt ID | Q921I1 |
| Accession | Q61247 |
| Product Details | |
|---|---|
| Expression Host | Human Cells |
| Species | Mouse |
| Tag | C-6His |
| Molar Mass | 53.2 kDa |
| Sequence | Ser 28-Ser 99 |
| Background |
|---|
| Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 20% Glycerol,1 mM DTT, pH8.0. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.