Recombinant Mouse PSGL-1/CD162 Protein (aa 42-307, Fc Tag)
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Recombinant Mouse PSGL-1/CD162 Protein (aa 42-307, Fc Tag)

Cat. No : CDRP-01097
size:
Target Information
Target Name PSGL-1/CD162
Synonyms P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG; CLA; PSGL1
UniProt ID Q8NBP7
Accession Q62170
Product Details
Expression Host HEK293 Cells
Species Mouse
Tag C-Fc
Molar Mass 54.7 kDa
Sequence Asn 23-Ala 500
Background
P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Properties
Purity >90% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.