Recombinant Mouse P-selectin/CD62P Protein (AVI & His Tag)
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Recombinant Mouse P-selectin/CD62P Protein (AVI & His Tag)

Cat. No : CDRP-01094
size:
Target Information
Target Name P-selectin/CD62P
Synonyms P-selectin; CD62 antigen-like family member P; Granule membrane protein 140;   GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM
UniProt ID Q8JZQ0
Accession Q01102
Product Details
Expression Host HEK293 Cells
Species Mouse
Tag C-AVI-His
Molar Mass 75.2 kDa
Sequence Glu 31-Arg 370
Background
P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P-selectin interacts with SNX17, PSGL1/SEPL, PODXL2, mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Properties
Purity >92% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.