Recombinant Mouse MMP12/MMP-12/HME Protein (His Tag)

Cat. No : CDRP-01064

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Target Information
Target Name	MMP12/MMP-12/HME
Synonyms	HME; ME; MME; MMP-12
UniProt ID	Q66HI4
Accession	P34960

Product Details
Expression Host	HEK293 Cells
Species	Mouse
Tag	C-6His
Molar Mass	53 kDa
Sequence	Trp 27-Lys 547

Background
Matrix metalloproteinase-12（MMP12） is a secreted protein. It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Background

Matrix metalloproteinase-12（MMP12） is a secreted protein. It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Properties
Purity	>98% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.