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Recombinant Mouse FSTL1 Protein (Fc Tag)
Cat. No : CDRP-00989
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Target Information | |
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Target Name | FSTL1 |
Synonyms | Follistatin-Related Protein 1; Follistatin-Like Protein 1; FSTL1; FRP |
UniProt ID | Q14012 |
Accession | Q62356 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Mouse |
Tag | C-Fc |
Molar Mass | 59.6 kDa |
Sequence | Gly 28-Lys 291 |
Background |
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Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGFβ1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.