Recombinant Mouse EphB4/HTK Protein (His Tag) (Active)
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Recombinant Mouse EphB4/HTK Protein (His Tag) (Active)

Cat. No : CDRP-00954
size:
Target Information
Target Name EphB4/HTK
Synonyms HTK; MYK1; TYRO11
UniProt ID Q10589
Accession P54761-1
Product Details
Expression Host HEK293 Cells
Species Mouse
Tag C-His
Molar Mass 59 kDa
Sequence Met 1-Thr 493
Application Functional ELISA
Background
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.