Recombinant Mouse CX3CL1/Fractalkine Protein (His Tag)
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Recombinant Mouse CX3CL1/Fractalkine Protein (His Tag)

Cat. No : CDRP-00922
size:
Target Information
Target Name CX3CL1/Fractalkine
Synonyms Fractalkine; C-X3-C Motif Chemokine 1; CX3C Membrane-Anchored Chemokine; Neurotactin; Small-Inducible Cytokine D1; CX3CL1; FKN; NTT; SCYD1
UniProt ID Q03405
Accession O35188
Product Details
Expression Host HEK293 Cells
Species Mouse
Tag C-6His
Molar Mass 34.3 kDa
Sequence Asp 19-Ser 182
Background
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in response to cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.
Properties
Purity >90% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.