Products
Online Inquiry
Recombinant Human/Mouse/Rat BDNF Protein (Active)
Cat. No : CDRP-00811
size:
| Target Information | |
|---|---|
| Target Name | BDNF |
| Synonyms | Brain-Derived Neurotrophic Factor; BDNF; Abrineurin |
| UniProt ID | P52793 |
| Accession | P23560 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human/Mouse/Rat |
| Tag | None |
| Molar Mass | 13 kDa |
| Sequence | Arg 453-Ser 1152 |
| Application | Functional ELISA |
| Background |
|---|
| Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF; NT-3 and NT-4; BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor; also known as p75). BDNF promotes the survival; growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. |
| Properties | |
|---|---|
| Purity | >90% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 250 mM NaCl, pH7.2. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.