Recombinant Human Vaspin/SerpinA12 Protein (His Tag)
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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Recombinant Human Vaspin/SerpinA12 Protein (His Tag)

Cat. No : CDRP-00767
size:
Target Information
Target Name Vaspin/SerpinA12
Synonyms Serpin A12; OL-64; Vaspin; Visceral Adipose-Specific Serpin; SERPINA12
UniProt ID P43652
Accession Q8IW75
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-His
Molar Mass 46.5 kDa
Sequence Ser 21-Glu 359
Background
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets; nine α-helices; and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity; insulin resistance; and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH7.5.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.