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Recombinant Human Vaspin/SerpinA12 Protein (GST Tag)
Cat. No : CDRP-00766
size:
Target Information | |
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Target Name | Vaspin/SerpinA12 |
Synonyms | Serpin A12; OL-64; Vaspin; Visceral Adipose-Specific Serpin; SERPINA12 |
UniProt ID | P43490 |
Accession | Q8IW75 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | N-GST |
Molar Mass | 71.4 kDa |
Sequence | Thr 24-Glu 481 |
Background |
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Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets; nine α-helices; and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity; insulin resistance; and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 160 mM NaCl, 0.2 mM PMSF, 1 mM DTT, 10% Glycerine, pH7.2. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.