Products
Online Inquiry
Recombinant Human TNFRSF1B/CD120b Protein (aa 288-461, His Tag)
Cat. No : CDRP-00710
size:
| Target Information | |
|---|---|
| Target Name | TNFRSF1B/CD120b |
| Synonyms | CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80 |
| UniProt ID | P35613-2 |
| Accession | P20333 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 19 kDa |
| Sequence | Ile 27-Ser 159 |
| Background |
|---|
| Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2; and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.