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Recombinant Human TGFB1/TGF-beta 1 Protein (His Tag)
Cat. No : CDRP-00647
size:
Target Information | |
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Target Name | TGFB1/TGF-beta 1 |
Synonyms | Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB; CED; DPD1; TGF-beta 1 |
UniProt ID | P28776 |
Accession | P01137 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | N-His |
Molar Mass | 41.3 & 12.8 kDa |
Sequence | Gln 28-Glu 480 |
Background |
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Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone; articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions; including the control of cell growth; cell proliferation; cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease. |
Properties | |
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Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine, 50 mM NaCl, pH4.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.