Recombinant Human STK4/MST1 Protein (His Tag) (Active)

Cat. No : CDRP-00607

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Target Information
Target Name	STK4/MST1
Synonyms	KRS2; MST1; TIIAC; YSK3
UniProt ID	P23560
Accession	Q13043-1

Product Details
Expression Host	Baculovirus-Insect Cells
Species	Human
Tag	N-His
Molar Mass	58 kDa
Sequence	Tyr 95-Tyr 146

Background
MST1 protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Background

MST1 protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Properties
Purity	>98% as determined by reducing SDS-PAGE.
Formulation	Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.