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Recombinant Human STAT3 Protein (His Tag)
Cat. No : CDRP-00606
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| Target Information | |
|---|---|
| Target Name | STAT3 |
| Synonyms | Signal Transducer and Activator of Transcription 3; Acute-Phase Response Factor; STAT3; APRF |
| UniProt ID | P23560 |
| Accession | P40763 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 21.8 kDa |
| Sequence | Asp 23-Pro 119 |
| Background |
|---|
| Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. |
| Properties | |
|---|---|
| Purity | >90% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.