Recombinant Human SOD2/Mn-SOD Protein (His Tag, Human Cells)

Cat. No : CDRP-00601

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Target Information
Target Name	SOD2/Mn-SOD
Synonyms	Superoxide Dismutase [Mn] Mitochondrial; SOD2
UniProt ID	P22934
Accession	P04179

Product Details
Expression Host	HEK293 Cells
Species	Human
Tag	C-6His
Molar Mass	23.2 kDa
Sequence	Ser 27-Asn 756

Background
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.

Background

Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.

Properties
Purity	>97% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH8.0.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.