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Recombinant Human Serum Amyloid A1/SAA1 Protein (His Tag)
Cat. No : CDRP-00582
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Target Information | |
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Target Name | Serum Amyloid A1/SAA1 |
Synonyms | Serum Amyloid A-1 Protein; SAA; SAA1 |
UniProt ID | P21589 |
Accession | P0DJI8 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | N-6His |
Molar Mass | 13.2 kDa |
Sequence | Gln 24-Thr 99 |
Background |
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Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance. |
Properties | |
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Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl,1 mM EDTA, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.