Recombinant Human SERPINB1/PI2 Protein (Baculovirus, His Tag)

Cat. No : CDRP-00562

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Target Information
Target Name	SERPINB1/PI2
Synonyms	Leukocyte elastase inhibitor; SERPINB1; Monocyte/neutrophil elastase inhibitor; M/NEI; Peptidase inhibitor 2; PI-2; PI2; EI; ELANH2; HEL-S-27; HEL57; LEI; MNEI
UniProt ID	P20160
Accession	P30740

Product Details
Expression Host	Baculovirus-Insect Cells
Species	Human
Tag	C-His
Molar Mass	44 kDa
Sequence	Lys 32-Asn 372

Background
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.

Background

SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.

Properties
Purity	>95% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH8.0.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.