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Recombinant Human SerpinA4/SERPINA4 Protein (His Tag)
Cat. No : CDRP-00559
size:
| Target Information | |
|---|---|
| Target Name | SerpinA4/SERPINA4 |
| Synonyms | Kallistatin; Kallikrein Inhibitor; Peptidase Inhibitor 4; PI-4; Serpin A4; SERPINA4; KST; PI4 |
| UniProt ID | P20109 |
| Accession | P29622 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 47.1 kDa |
| Sequence | Gln 31-Gln 692 |
| Background |
|---|
| Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity. |
| Properties | |
|---|---|
| Purity | >90% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 150 mM NaCl, 10 mM NaCl, pH8.0. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.