Recombinant Human SAA4 Protein (GST Tag)

Cat. No : CDRP-00540

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Target Information
Target Name	SAA4
Synonyms	Serum Amyloid A-4 Protein; Constitutively Expressed Serum Amyloid A Protein; C-SAA; SAA4; CSAA
UniProt ID	P18206
Accession	P35542

Product Details
Expression Host	E.coli
Species	Human
Tag	N-GST
Molar Mass	39.8kDa
Sequence	Met 1-Ala 482

Background
SAA4 is a member of the SAA family. SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice. It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.

Background

SAA4 is a member of the SAA family. SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice. It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.

Properties
Purity	>95% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from sterile PBS, 0.5% Triton X-100, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.