Recombinant Human RBP4 Protein

Cat. No : CDRP-00524

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Target Information
Target Name	RBP4
Synonyms	RDCCAS; Retinol-Binding Protein 4; Plasma Retinol-Binding Protein; PRBP; RBP; RBP4
UniProt ID	P16860
Accession	NP_006735.2

Product Details
Expression Host	E.coli
Species	Human
Tag	None
Molar Mass	21.2 kDa
Sequence	Gln 31-Gln 152 & Ser 153-Gln 692

Background
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue; and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma; the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.

Background

Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue; and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma; the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.

Properties
Purity	>90% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 10 mM CaCl₂, 150 mM NaCl, pH7.5.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.