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Recombinant Human PRCP Protein (His Tag)
Cat. No : CDRP-00502
size:
| Target Information | |
|---|---|
| Target Name | PRCP |
| Synonyms | Lysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP |
| UniProt ID | P16118 |
| Accession | P42785 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 54.5 kDa |
| Sequence | Ser 27-Ala 146 |
| Background |
|---|
| Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein. |
| Properties | |
|---|---|
| Purity | >96% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc, 150 mM NaCl,10% Glycerol, pH4.5. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.