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Recombinant Human PON3/Paraoxonase 3 Protein (50 Ser/Asn, His Tag)
Cat. No : CDRP-00490
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Target Information | |
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Target Name | PON3/Paraoxonase 3 |
Synonyms | PON3 |
UniProt ID | P15692 |
Accession | Q15166-1 |
Product Details | |
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Expression Host | Baculovirus-Insect Cells |
Species | Human |
Tag | N-His |
Molar Mass | 42 kDa |
Sequence | Lys 32-Asn 372 |
Background |
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KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.