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Recombinant Human Peroxiredoxin 3/PRDX3 Protein
Cat. No : CDRP-00457
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| Target Information | |
|---|---|
| Target Name | Peroxiredoxin 3/PRDX3 |
| Synonyms | Thioredoxin-Dependent Peroxide Reductase Mitochondrial; Antioxidant Protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog; PRDX3; AOP1 |
| UniProt ID | P13726 |
| Accession | P30048 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | None |
| Molar Mass | 21.6 kDa |
| Sequence | Ser 87-Thr 211 |
| Background |
|---|
| Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH8.0. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.