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Recombinant Human Periostin/OSF-2 Protein (His Tag)
Cat. No : CDRP-00452
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Target Information | |
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Target Name | Periostin/OSF-2 |
Synonyms | Osteoblast-specific factor 2; OSF-2; POSTN; Periostin; PDLPOSTN; periostin; PN |
UniProt ID | P13504 |
Accession | Q15063 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-6His |
Molar Mass | 85.6 kDa |
Sequence | Gln 19-Leu 353 |
Background |
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Osteoblast-Specific Factor OSF-2 (POSTN, Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. Periostin is a disulfide linked 90kDa bone adhesion protein secreted by osteoblasts and osteoblast-like cell lines and the protein is an attachment agent for osteoblasts. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells. |
Properties | |
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Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.