Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)

Cat. No : CDRP-00386

size:

Target Information
Target Name	Natriuretic Peptides B/NPPB
Synonyms	Natriuretic Peptides B; Gamma-Brain Natriuretic Peptide; NPPB
UniProt ID	P0DJI9
Accession	P16860

Product Details
Expression Host	E.coli
Species	Human
Tag	N-His
Molar Mass	14.2 kDa
Sequence	Ser 28-Ser 99

Background
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

Background

Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

Properties
Purity	>96% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 20% Glycerol, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.