Recombinant Human MMP-9 Protein (His Tag)
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Recombinant Human MMP-9 Protein (His Tag)

Cat. No : CDRP-00364
size:
Target Information
Target Name MMP-9
Synonyms Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9; CLG4B; GELB; MANDP2
UniProt ID P09038
Accession NP_004985.2
Product Details
Expression Host Human Cells
Species Human
Tag C-6His
Molar Mass 77.4 kDa
Sequence Ser 61-Gln 273
Background
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 2 mM CaCl2, 150 mM NaCl, 0.05% Brij35(w/v), pH7.5.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.