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Recombinant Human MMP-9 Protein (His Tag)
Cat. No : CDRP-00364
size:
Target Information | |
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Target Name | MMP-9 |
Synonyms | Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9; CLG4B; GELB; MANDP2 |
UniProt ID | P09038 |
Accession | NP_004985.2 |
Product Details | |
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Expression Host | Human Cells |
Species | Human |
Tag | C-6His |
Molar Mass | 77.4 kDa |
Sequence | Ser 61-Gln 273 |
Background |
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Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 2 mM CaCl2, 150 mM NaCl, 0.05% Brij35(w/v), pH7.5. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.