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Recombinant Human MMP-3 Protein (His Tag)
Cat. No : CDRP-00355
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Target Information | |
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Target Name | MMP-3 |
Synonyms | Stromelysin-1; SL-1; Matrix metalloproteinase-3; Transin-1; MMP3; STMY1; CHDS6; MMP-3; SL-1; STMY; STR1 |
UniProt ID | P08962 |
Accession | P08254 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-His |
Molar Mass | 53.26 kDa |
Sequence | Ser 46-Ile 113 |
Background |
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MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling. [3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 10% Glycerol, pH7.5. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.