Recombinant Human MMP-3 Protein (His Tag)
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Recombinant Human MMP-3 Protein (His Tag)

Cat. No : CDRP-00355
size:
Target Information
Target Name MMP-3
Synonyms Stromelysin-1; SL-1; Matrix metalloproteinase-3; Transin-1; MMP3; STMY1; CHDS6; MMP-3; SL-1; STMY; STR1
UniProt ID P08962
Accession P08254
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-His
Molar Mass 53.26 kDa
Sequence Ser 46-Ile 113
Background
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling. [3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 10% Glycerol, pH7.5.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.