Recombinant Human LIMP-2/LIMPII Protein (His & Fc Tag) (Active)
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Recombinant Human LIMP-2/LIMPII Protein (His & Fc Tag) (Active)

Cat. No : CDRP-00306
size:
Target Information
Target Name LIMP-2/LIMPII
Synonyms Lysosome Membrane Protein 2; 85 kDa Lysosomal Membrane Sialoglycoprotein; LGP85; CD36 Antigen-Like 2; Lysosome Membrane Protein II; LIMP II; Scavenger Receptor Class B Member 2; CD36; SCARB2; CD36L2; LIMPII; AMRF; CD36L2; EPM4; HLGP85; LGP85; SR-BII
UniProt ID P07091
Accession NP_005497.1
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-His & Fc
Molar Mass 74.4 kDa
Sequence Met 1-Ser 130
Application Functional ELISA
Background
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.