Recombinant Human Interleukin-13/IL-13 Protein (Fc Tag) (Active)
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Recombinant Human Interleukin-13/IL-13 Protein (Fc Tag) (Active)

Cat. No : CDRP-00259
size:
Target Information
Target Name Interleukin-13/IL-13
Synonyms ALRH; IL-13; P600; IL13
UniProt ID P04179
Accession AAK53823.1
Product Details
Expression Host HEK293 Cells
Species Human
Tag N-hFc
Molar Mass 39 kDa
Sequence Met 1-Leu 609
Application Functional ELISA
Background
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.