Products
Online Inquiry
Recombinant Human Interleukin-11/IL-11 Protein
Cat. No : CDRP-00256
size:
Target Information | |
---|---|
Target Name | Interleukin-11/IL-11 |
Synonyms | Interleukin-11; IL-11; Adipogenesis Inhibitory Factor; AGIF; Oprelvekin; IL11 |
UniProt ID | P04118 |
Accession | P20809 |
Product Details | |
---|---|
Expression Host | P. pastoris |
Species | Human |
Tag | None |
Molar Mass | 19 kDa |
Sequence | Arg 41-Pro 945 |
Background |
---|
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. |
Properties | |
---|---|
Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 2% Glycine, pH7.2. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.