Recombinant Human IL1RL1/ST2 Protein (His Tag)
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Recombinant Human IL1RL1/ST2 Protein (His Tag)

Cat. No : CDRP-00202
size:
Target Information
Target Name IL1RL1/ST2
Synonyms DER4; FIT-1; IL1RL1; IL33R; IL‑1 R4; ST2; ST2L; ST2V; T1
UniProt ID P02749
Accession Q01638-2
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-6His
Molar Mass 36 kDa
Sequence Asn 49-Ser 162
Background
Interleukin 1 receptor-like 1(IL1RL1) is a member of the interleukin-1 receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a receptor for interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 cytokine production, it directly implicated in the progression of cardiac disease.
Properties
Purity >90% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.