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Recombinant Human IL-4 Protein
Cat. No : CDRP-00220
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| Target Information | |
|---|---|
| Target Name | IL-4 |
| Synonyms | Interleukin-4; IL4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra |
| UniProt ID | P02771 |
| Accession | NP_000580.1 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | N-His |
| Molar Mass | 15 kDa |
| Sequence | Met 1-Arg 278 |
| Background |
|---|
| Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% mannitol, 0.01% tween-80. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.