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Recombinant Human IL-1Ra Protein
Cat. No : CDRP-00195
size:
| Target Information | |
|---|---|
| Target Name | IL-1Ra |
| Synonyms | Interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; ICIL-1RA; IL1 inhibitor; Anakinra; IL1RN; IL1F3; IL1RA |
| UniProt ID | P02743 |
| Accession | NP_776214.1 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | N-His |
| Molar Mass | 19.4 kDa |
| Sequence | Met 1-Asn 332 |
| Background |
|---|
| Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% mannitol, 0.01% tween-80. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.