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Recombinant Human IGFBP3 Protein (His Tag)
Cat. No : CDRP-00164
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Target Information | |
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Target Name | IGFBP3 |
Synonyms | IBP-3; IGF-binding protein 3; IGFBP-3 |
UniProt ID | P01584 |
Accession | P17936 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-His |
Molar Mass | 32.5 kDa |
Sequence | Pro 2-Lys 97 |
Background |
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IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity. Promotes testicular germ cell apoptosis. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile PBS, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.