Recombinant Human Hepcidin/HAMP Protein (GST Tag)

Cat. No : CDRP-00126

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Target Information
Target Name	Hepcidin/HAMP
Synonyms	Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1
UniProt ID	P01019
Accession	P81172

Product Details
Expression Host	E.coli
Species	Human
Tag	N-GST
Molar Mass	29.2 kDa
Sequence	Trp 22-Pro 556

Background
Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family. It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

Background

Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family. It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

Properties
Purity	>98% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, 50%Glycerol, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.