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Recombinant Human GSTP1 Protein
Cat. No : CDRP-00104
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Target Information | |
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Target Name | GSTP1 |
Synonyms | Glutathione S-transferase P; GSTP1; GST class-pi; GSTP1-1; FAEES3; GST3 |
UniProt ID | P00450 |
Accession | P09211 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | None |
Molar Mass | 23.5 kDa |
Sequence | Ser 27-Ile 151 |
Background |
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Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 10% Glycerol, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.