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Recombinant Human GSK3α Protein
Cat. No : CDRP-00102
size:
| Target Information | |
|---|---|
| Target Name | GSK3α |
| Synonyms | Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A ; GSK3A |
| UniProt ID | O95971 |
| Accession | NP_063937.2 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | N-His |
| Molar Mass | 39.4 kDa |
| Sequence | Met 1-Asn 599 |
| Background |
|---|
| Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% mannitol, 0.01% tween-80. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.