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Recombinant Human GPD1/GDP-C Protein (E.coli, His Tag)
Cat. No : CDRP-00092
size:
Target Information | |
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Target Name | GPD1/GDP-C |
Synonyms | Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic; GPD-C; GPDH-C; GPD1; HTGTI |
UniProt ID | O95760 |
Accession | P21695 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | N-His |
Molar Mass | 39.4 kDa |
Sequence | Met 1-Ala 248 |
Background |
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GPD1; also known as glycerolphosphate dehydrogenase 1; is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion ofdihydroxyacetone phosphate (DHAP); thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile; GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile 50 mM Tris, 10% Glycerol, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.