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Recombinant Human GITRL Protein (His Tag)
Cat. No : CDRP-00086
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Target Information | |
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Target Name | GITRL |
Synonyms | Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46; Ghrelin |
UniProt ID | O95445 |
Accession | Q9UNG2 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-His |
Molar Mass | 14.6 kDa |
Sequence | Pro 30-Trp 97 |
Background |
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Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells . Regulates migration of monocytes from the splenic reservoir to sites of inflammation. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile PBS, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.