Recombinant Human GAS6 Protein (C-6His)
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Recombinant Human GAS6 Protein (C-6His)

Cat. No : CDRP-00076
size:
Target Information
Target Name GAS6
Synonyms AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; Gas6; GAS-6; growth arrest-specific 6; growth arrest-specific protein 6
UniProt ID O89098
Accession Q14393
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-6His
Molar Mass 72.7 kDa
Sequence Thr 33-His 682
Background
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.