Products
Online Inquiry
Recombinant Human FTL Protein (His Tag)
Cat. No : CDRP-00067
size:
Target Information | |
---|---|
Target Name | FTL |
Synonyms | Ferritin heavy chain; FTH1; FTH; FTHL6; Ferritin H subunit; Cell proliferation-inducing gene 15 protein; FHC; HFE5; PIG15 |
UniProt ID | O70156 |
Accession | P02792 |
Product Details | |
---|---|
Expression Host | E.coli |
Species | Human |
Tag | N-6His |
Molar Mass | 24.5 kDa |
Sequence | Gln 21-Asn 200 |
Background |
---|
Ferritin is a large; iron-storage heteropolymeric protein;which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin has oligomer of 24 subunits and two types of subunits including light chain(FTL) and heavy chain. Ferritin can remove Fe (Ⅱ) from solution in the presence of oxygen and is very important for iron homeostasis. Iron is absorbed in the ferrous form and deposited as ferric hydroxides after oxidation. Iron is first oxidized to the ferric state for storage as ferric oxyhdroxide whithin the protein shell of ferritin. Thus; ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. Ferritin also plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. |
Properties | |
---|---|
Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 250 mM NaCl,1 mM EDTA, pH9.5. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.