Recombinant Human FGL1 Protein (mFc Tag) (Active)

Cat. No : CDRP-00975

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Target Information
Target Name	FGL1
Synonyms	Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
UniProt ID	Q13410
Accession	Q08830

Product Details
Expression Host	HEK293 Cells
Species	Human
Tag	C-mFc
Molar Mass	60.6 kDa
Sequence	Gln 35-Gln 155 & Ser 156-Gln 692
Application	Functional ELISA

Background
Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

Background

Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

Properties
Purity	>90% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, 5% Thehalose, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.