Recombinant Human FGF21 Protein (His Tag)
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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Recombinant Human FGF21 Protein (His Tag)

Cat. No : CDRP-00035
size:
Target Information
Target Name FGF21
Synonyms Fibroblast growth factor 21; FGF-21; UNQ3115; PRO10196
UniProt ID O15123
Accession NP_061986.1
Product Details
Expression Host E.coli
Species Human
Tag N-His
Molar Mass 20.2 kDa
Sequence Ala 103-Val 203
Background
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.
Properties
Purity >70% as determined by reducing SDS-PAGE.
Formulation Lyophilized from 50 mM Tris, 10% Glycerol, 0.05% Brij 35, pH8.0.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.