Recombinant Human Erythropoietin R/EPOR Protein (Fc Tag)

Cat. No : CDRP-00580

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Target Information
Target Name	Erythropoietin R/EPOR
Synonyms	EpoR; EPO-R; Erythropoietin R; erythropoietin receptor; MGC138358; Platelet Receptor EPO-R
UniProt ID	P21589
Accession	P19235

Product Details
Expression Host	HEK293 Cells
Species	Human
Tag	C-Fc
Molar Mass	54.5 kDa
Sequence	Gly 311-Arg 731

Background
Erythropoietin (Epo); a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

Background

Erythropoietin (Epo); a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

Properties
Purity	>93% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.