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Recombinant Human EPO Receptor/EPOR Protein (Fc Tag) (Active)
Cat. No : CDRP-00024
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Target Information | |
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Target Name | EPO Receptor/EPOR |
Synonyms | EPO-R |
UniProt ID | O00622 |
Accession | NP_000112.1 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-hFc |
Molar Mass | 51 kDa |
Sequence | Met 1-Arg 209 |
Application | Functional ELISA |
Background |
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Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile PBS, 8% sucrose, 0.5% Tween-20, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.