Recombinant Human EPO Receptor/EPOR Protein (Fc Tag) (Active)
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Recombinant Human EPO Receptor/EPOR Protein (Fc Tag) (Active)

Cat. No : CDRP-00024
size:
Target Information
Target Name EPO Receptor/EPOR
Synonyms EPO-R
UniProt ID O00622
Accession NP_000112.1
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-hFc
Molar Mass 51 kDa
Sequence Met 1-Arg 209
Application Functional ELISA
Background
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, 8% sucrose, 0.5% Tween-20, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.