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Recombinant Human Ephrin-B2/EFNB2 Protein (His Tag) (Active)
Cat. No : CDRP-00853
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| Target Information | |
|---|---|
| Target Name | Ephrin-B2/EFNB2 |
| Synonyms | Ephrin-B2; EPH-Related Receptor Tyrosine Kinase Ligand 5; LERK-5; HTK Ligand; HTK-L; EFNB2; EPLG5; HTKL; LERK5 |
| UniProt ID | P55916 |
| Accession | P52799 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 23.2 kDa |
| Sequence | Ala 27-Arg 242 |
| Application | Functional ELISA |
| Background |
|---|
| Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons. |
| Properties | |
|---|---|
| Purity | >85% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.2. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.